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VOL. 8, ISSUE 2 (2026)
Antimicrobial and phytochemical properties of grape fruit mesocarp and juice against Some Pathogenic Microorganisms
Authors
Anumihe O C, Okwuchi Obinna P C, Edward O, Onyewuenyi N P, Etoamaihe U, Dickson C A, Okoye C I
Abstract
This study investigated the antimicrobial and
phytochemical properties of grape fruit mesocarp and juice against some
pathogenic microorganisms. The ripe fruits of Citrus paradisi
(grapefruit) were collected after identification by a Botanist. The juice was
squeezed out while the fruit mesocarp was extracted using methanol.
Phytochemical sereening revealed the presence of saponins, athranoids, tannins,
alkaloids and phenols were detected with grape juice while anthranoids,
phlobatannins, cardiac glycosides, alkaloids and phenols were detected with
grape mesocarp extract. Agar well diffusion technique was adopted in the
determination of the antimicrobial activities of the extracts against Salmonella,
Escherichia, Pseudomonas, Enterococcus and Candida species. Zones of
inhibition recorded ranged from 16mm to 24mm with grape fruit mesocarp extract
and 12mm to 22mm with grape fruit juice. Inhibitory effect recorded ranged from
125mg/ml to 250mg/ml with grape fruit mesocarp extract and 250mg/ml to 500mg/
ml with grape fruit juice. Bactericidal activity was recorded with grape fruit
mesocarp extract at 500mg/ml against Salmonella and Escherichia
species. Grape fruit juice showed bactericidal effect at 500mg/ml against Enterococcus
species. The extracts showed bacteriostatic and fungiostatic effect against
the other test organisms. The result of the phytochemical screening of grape
fruit mesocarp and juice suggests the possible pharmacological importance of
this plant part. The antimicrobial activity recorded against the test organisms
showed that the plant extract is effective against Escherichia species
and Salmonella species. The use of this plant part in traditional and
pharmaceutical industries could be of health improvement through infection
prevention and management.
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Pages:108-112
How to cite this article:
Anumihe O C, Okwuchi Obinna P C, Edward O, Onyewuenyi N P, Etoamaihe U, Dickson C A, Okoye C I "Antimicrobial and phytochemical properties of grape fruit mesocarp and juice against Some Pathogenic Microorganisms". International Journal of Biotechnology and Microbiology, Vol 8, Issue 2, 2026, Pages 108-112
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